Trifluoromethanesulfonic anhydride
| Product Type |
Pesticide products |
| Product Name |
Trifluoromethanesulfonic anhydride |
| CAS NO. |
358-23-6 |
| Detail |
| Common name: |
Triflic anhydride; Trifluoromethanesulphonic anhydride |
| Alternative name: |
Tf2O |
| CAS No.: |
358-23-6 |
| Appearance: |
Colorless to light brown transparent liquid with a stimulating odor. |
| Basic information: |
Trifluoromethanesulfonic anhydride is widely used in the synthesis of alkyl and vinyl trifluoromethyl sulfonates. In chemical and pharmaceutical synthesis, catalytic applications are made with trifluoroacetic acid, acids, and esters. |
| Structural formula: |
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| Core uses |
Inert hydroxyl groups are converted into trifluoromethanesulfonate (-OTf) by reacting with alcohols or phenols.
The leaving capacity of -OTf is tens of thousands of times stronger than that of the commonly used p-toluenesulfonate (-OTs), enabling reactions that originally required intense conditions to proceed in a mild environment.
Convert carboxylic acids into highly reactive mixed anhydrides.
This mixed anhydride does not require separation and can directly react with amines or alcohols to efficiently form amides or esters.
The combination system with weak bases (such as triethylamine) is a very mild and efficient dehydrating agent, which can dehydrate primary amides and convert them into nitriles. |
| Picture: |
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